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Modelling and simulating generic RNA-Seq experiments with the flux simulator

High-throughput sequencing of cDNA libraries constructed from cellular RNA complements (RNA-Seq) naturally provides a digital quantitative measurement for every expressed RNA molecule. Nature, impact and mutual interference of biases in different experimental setups are, however, still poorly unders...

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Detalhes bibliográficos
Main Authors: Griebel, Thasso, Zacher, Benedikt, Ribeca, Paolo, Raineri, Emanuele, Lacroix, Vincent, Guigó, Roderic, Sammeth, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488205/
https://ncbi.nlm.nih.gov/pubmed/22962361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks666
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