A peptide derived from the highly conserved protein GAPDH is involved in tissue protection by different antifungal strategies and epithelial immunomodulation

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) plays an important role in glycolysis but also in non-metabolic processes, including transcription activation and apoptosis. We report the isolation of an hGAPDH (2-32) fragment peptide from human placental tissue exhibiting antimicrobial activity. Th...

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Detalhes bibliográficos
Main Authors: Wagener, Jeanette, Schneider, Josef J., Baxmann, Susann, Kalbacher, Hubert, Borelli, Claudia, Nuding, Sabine, Küchler, Robert, Wehkamp, Jan, Kaeser, Matthias D., Mailänder-Sanchez, Daniela, Braunsdorf, Christina, Hube, Bernhard, Schild, Lydia, Forssmann, Wolf-Georg, Korting, Hans-Christian, Liepke, Cornelia, Schaller, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488162/
https://ncbi.nlm.nih.gov/pubmed/22832495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.254
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