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PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors

The developmental origin of adipose tissue and what controls its distribution is poorly understood. By linage tracing and gene expression analysis in mice, we provide evidence that mesenchymal precursors expressing Myf5—which are thought to give rise only to brown adipocytes and skeletal muscle—also...

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Autors principals: Sanchez-Gurmaches, Joan, Hung, Chien-Min, Sparks, Cynthia A., Tang, Yuefeng, Li, Huawei, Guertin, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488151/
https://ncbi.nlm.nih.gov/pubmed/22940198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.08.003
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