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Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients

BACKGROUND: Individuals with implanted mechanical valve prostheses require lifelong anticoagulation therapy with warfarin. The narrow therapeutic index of warfarin makes it difficult to dose and maintain proper anticoagulation. A number of single nucleotide polymorphisms (SNPs) affecting vitamin K o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Jie-Hui, Ma, Guo-Guo, Zhu, Shu-Qiang, Yan, Hao, Wu, Yong-Bing, Xu, Jian-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487995/
https://ncbi.nlm.nih.gov/pubmed/23013706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-7-97
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