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Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial

BACKGROUND: Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, randomized controlled trial in Mbarara, Uganda demonstrated that artemether-lumefantrine (AL) is not inferior to quinine t...

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Main Authors: Muehlenbachs, Atis, Nabasumba, Carolyn, McGready, Rose, Turyakira, Eleanor, Tumwebaze, Benon, Dhorda, Mehul, Nyehangane, Dan, Nalusaji, Aisha, Nosten, Franois, Guerin, Philippe J, Piola, Patrice
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487992/
https://ncbi.nlm.nih.gov/pubmed/22554092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-150
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