Genetic polymorphism and natural selection in the C-terminal 42 kDa region of merozoite surface protein-1 among Plasmodium vivax Korean isolates

BACKGROUND: The carboxy-terminal 42 kDa region of Plasmodium vivax merozoite surface protein-1 (PvMSP-1(42)) is a leading candidate antigen for blood stage vaccine development. However, this region has been observed to be highly polymorphic among filed isolates of P. vivax. Therefore it is important...

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Main Authors: Kang, Jung-Mi, Ju, Hye-Lim, Kang, Yoo-Mi, Lee, Dong-Hyun, Moon, Sung-Ung, Sohn, Woon-Mok, Park, Jae-Won, Kim, Tong-Soo, Na, Byoung-Kuk
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487983/
https://ncbi.nlm.nih.gov/pubmed/22709605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-206
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