Caveolin-1 reduces HIV-1 infectivity by restoration of HIV Nef mediated impairment of cholesterol efflux by apoA-I

BACKGROUND: HIV infection results in inhibited cholesterol efflux by apolipoprotein A-I (apoA-I) in macrophages, and this impairment involves Nef mediated down-regulation and redistribution of ATP-binding cassette transporter A1 (ABCA-1). We investigated the effect of caveolin-1 (Cav-1) on the chole...

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Bibliografiska uppgifter
Huvudupphovsmän: Lin, Shanshan, Nadeau, Peter E, Wang, Xiaomei, Mergia, Ayalew
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487900/
https://ncbi.nlm.nih.gov/pubmed/23067370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-85
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