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Usefulness of antibody index assessment in cerebrospinal fluid from patients negative for total-IgG oligoclonal bands

BACKGROUND: Testing for cerebrospinal fluid (CSF)-restricted oligoclonal bands (OCB) by isoelectric focusing is used to detect intrathecally produced total IgG. By contrast, antibody indices (AI) are assessed to test for intrathecally produced antigen-specific IgG. A number of previous cases reports...

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Bibliographic Details
Main Authors: Jarius, Sven, Eichhorn, Peter, Wildemann, Brigitte, Wick, Manfred
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487855/
https://ncbi.nlm.nih.gov/pubmed/22849518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-9-14
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