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In Vivo Anti-HIV Activity of the Heparin-Activated Serine Protease Inhibitor Antithrombin III Encapsulated in Lymph-Targeting Immunoliposomes

Endogenous serine protease inhibitors (serpins) are anti-inflammatory mediators with multiple biologic functions. Several serpins have been reported to modulate HIV pathogenesis, or exhibit potent anti-HIV activity in vitro, but the efficacy of serpins as therapeutic agents for HIV in vivo has not y...

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Bibliografiske detaljer
Main Authors: Asmal, Mohammed, Whitney, James B., Luedemann, Corinne, Carville, Angela, Steen, Robert, Letvin, Norman L., Geiben-Lynn, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487854/
https://ncbi.nlm.nih.gov/pubmed/23133620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048234
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