Doxorubicin Influences the Expression of Glucosylceramide Synthase in Invasive Ductal Breast Cancer

INTRODUCTION: Glucosylceramide synthase (GCS) is one enzyme that provides a major route for ceramide clearance. Recent evidence has indicated an important role for GCS in multidrug resistance (MDR) tumors. Doxorubicin (DOX)can modulate the expression of GCS in leukemia and ovary cell lines. However,...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaofang, Wu, Xiaojuan, Su, Peng, Gao, Yongsheng, Meng, Bin, Sun, Yanlin, Li, Li, Zhou, Zhiqiang, Zhou, Gengyin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487728/
https://ncbi.nlm.nih.gov/pubmed/23133636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048492
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