Acquisition of a multifunctional TNFα/iNOS-producing IgA(+) plasma cell phenotype in the gut

The largest mucosal surface in the body is in the gastrointestinal (GI) tract, a location that is heavily colonized by normally harmless microbes. A key mechanism required for maintaining a homeostatic balance between this microbial burden and the lymphocytes that densely populate the GI tract is th...

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Detalhes bibliográficos
Main Authors: Fritz, Jörg H., Rojas, Olga Lucia, Simard, Nathalie, McCarthy, Doug, Hapfelmeier, Siegfried, Rubino, Stephen, Robertson, Susan J., Larijani, Mani, Gosselin, Jean, Ivanov, Ivaylo I., Martin, Alberto, Casellas, Rafael, Philpott, Dana J., Girardin, Stephen E., McCoy, Kathy D., Macpherson, Andrew J., Paige, Christopher J., Gommerman, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487691/
https://ncbi.nlm.nih.gov/pubmed/22158124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10698
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