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Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis

Pancreatic cancer remains a leading cause of death despite its relatively low incidence. As in many other solid tumors, angiogenesis is critical to the growth and metastasis of this cancer. Through serial in vivo passages in mice, we have developed a highly aggressive variant of human pancreatic can...

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Autori principali: McElroy, Michele K., Kaushal, Sharmeela, Cao, Hop S. Tran, Moossa, A.R., Talamini, Mark A., Hoffman, Robert M., Bouvet, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487474/
https://ncbi.nlm.nih.gov/pubmed/19584238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0122
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