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Upregulation of thrombospondin-1 and angiogenesis in an aggressive human pancreatic cancer cell line selected for high metastasis

Pancreatic cancer remains a leading cause of death despite its relatively low incidence. As in many other solid tumors, angiogenesis is critical to the growth and metastasis of this cancer. Through serial in vivo passages in mice, we have developed a highly aggressive variant of human pancreatic can...

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Detalhes bibliográficos
Main Authors: McElroy, Michele K., Kaushal, Sharmeela, Cao, Hop S. Tran, Moossa, A.R., Talamini, Mark A., Hoffman, Robert M., Bouvet, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487474/
https://ncbi.nlm.nih.gov/pubmed/19584238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0122
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