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MicroRNA-125b transforms myeloid cell lines by repressing multiple mRNA

BACKGROUND: We previously described a t(2;11)(p21;q23) chromosomal translocation found in patients with myelodysplasia or acute myeloid leukemia that leads to over-expression of the microRNA miR-125b, and we showed that transplantation of mice with murine stem/progenitor cells overexpressing miR-125...

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Detalhes bibliográficos
Main Authors: Bousquet, Marina, Nguyen, Diu, Chen, Cynthia, Shields, Lauren, Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487446/
https://ncbi.nlm.nih.gov/pubmed/22689670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.061515
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