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Differentiation of the fast Na+ channel in embryonic heart cells: interaction of the channel with neurotoxins.

The sensitivity of embryonic cardiac cells to tetrodotoxin (TTX) increases with age. At the early embryonic stage, the maximum upstroke velocity is not affected by the presence of TTX. In the course of both in ovo and in vitro development, this velocity reaches an adult-like value of 90-120 V/sec, w...

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Detalhes bibliográficos
Main Authors: Renaud, J F, Romey, G, Lombet, A, Lazdunski, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC348742/
https://ncbi.nlm.nih.gov/pubmed/6117856
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