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Cell-mediated delivery of glucocorticoids from thiol-ene hydrogels

Thiol-ene-based poly(ethylene glycol) (PEG) hydrogels provide a unique functional platform for the sustained and localized delivery of bioactive small molecules like glucocorticoids. As a proof of concept, the synthetic glucocorticoid Dexamethasone (Dex) was conjugated to the N-terminus of a matrix...

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Autors principals: Yang, Chun, Mariner, Peter D., Nahreini, Jhenya N., Anseth, Kristi S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487401/
https://ncbi.nlm.nih.gov/pubmed/22902591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.08.002
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