Peroxisome Proliferator–Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia

BACKGROUND: Data conflict with regard to whether peroxisome proliferator–activated receptor-α agonism suppresses inflammation in humans. We hypothesized that in healthy adults peroxisome proliferator–activated receptor-α agonism with fenofibrate would blunt the induced immune responses to endotoxin...

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Autori principali: Mulvey, Claire K., Ferguson, Jane F., Tabita-Martinez, Jennifer, Kong, Stephanie, Shah, Rhia Y., Patel, Parth N., Master, Stephen R., Usman, M Haris U., Propert, Kathleen J., Shah, Rachana, Mehta, Nehal N., Reilly, Muredach P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487364/
https://ncbi.nlm.nih.gov/pubmed/23130172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.002923
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