AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes

Deletions involving the Y chromosome’s AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the region have been reported, but their population genetics are largely unexplored. We assessed the deletions’ prevalence...

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Autori principali: Rozen, Steven G., Marszalek, Janet D., Irenze, Kathryn, Skaletsky, Helen, Brown, Laura G., Oates, Robert D., Silber, Sherman J., Ardlie, Kristin, Page, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487143/
https://ncbi.nlm.nih.gov/pubmed/23103232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.09.003
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