AZFc Deletions and Spermatogenic Failure: A Population-Based Survey of 20,000 Y Chromosomes

Deletions involving the Y chromosome’s AZFc region are the most common known genetic cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the region have been reported, but their population genetics are largely unexplored. We assessed the deletions’ prevalence...

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Detalhes bibliográficos
Main Authors: Rozen, Steven G., Marszalek, Janet D., Irenze, Kathryn, Skaletsky, Helen, Brown, Laura G., Oates, Robert D., Silber, Sherman J., Ardlie, Kristin, Page, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487143/
https://ncbi.nlm.nih.gov/pubmed/23103232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.09.003
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