Identification of IL18RAP/IL18R1 and IL12B as Leprosy Risk Genes Demonstrates Shared Pathogenesis between Inflammation and Infectious Diseases

Of eight leprosy susceptibility loci identified by genome-wide association studies, five have been implicated in Crohn disease, suggesting a common genetic fingerprint between leprosy and inflammatory bowel disease (IBD). Here, we conducted a multiple-stage genetic association study of 133 IBD susce...

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Autori principali: Liu, Hong, Irwanto, Astrid, Tian, Hongqing, Fu, Xi'an, Yu, Yongxiang, Yu, Gongqi, Low, Huiqi, Chu, Tongsheng, Li, Yi, Shi, Benqing, Chen, Mingfei, Sun, Yonghu, Yuan, Chunying, Lu, Nan, You, Jiabao, Bao, Fangfang, Li, Jinghui, Liu, Jian, Liu, Huaxu, Liu, Dianchang, Yu, Xiulu, Zhang, Lin, Yang, Qing, Wang, Na, Niu, Guiye, Ma, Shanshan, Zhou, Yan, Wang, Chuan, Chen, Shumin, Zhang, Xuejun, Liu, Jianjun, Zhang, Furen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2012
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487119/
https://ncbi.nlm.nih.gov/pubmed/23103228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.09.010
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