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Direct Signaling Between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

Interactions of cancer cells with the primary tumor microenvironment are important determinants of cancer progression towards metastasis but it is unknown whether additional prometastatic signals are provided during the intravascular transit to the site of metastasis. Here, we show that platelet-tum...

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Hlavní autoři: Labelle, Myriam, Begum, Shahinoor, Hynes, Richard O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487108/
https://ncbi.nlm.nih.gov/pubmed/22094253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.09.009
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