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Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.

Acycloguanosine [9-(2-hydroxyethoxymethyl)guanine; acyclo-Guo] is a potent inhibitor of herpes simplex viruses (HSV); it is selectively phosphorylated in virus-infected cells. In order to define those viral functions that may mediate resistance to acyclo-Guo, the drug sensitivities of temperature-se...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Schnipper, L E, Crumpacker, C S
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1980
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246532/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2270
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