Embryos of Robertsonian Translocation Carriers Exhibit a Mitotic Interchromosomal Effect That Enhances Genetic Instability during Early Development

Balanced chromosomal rearrangements represent one of the most common forms of genetic abnormality affecting approximately 1 in every 500 (0.2%) individuals. Difficulties processing the abnormal chromosomes during meiosis lead to an elevated risk of chromosomally abnormal gametes, resulting in high r...

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Detaylı Bibliyografya
Asıl Yazarlar: Alfarawati, Samer, Fragouli, Elpida, Colls, Pere, Wells, Dagan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486902/
https://ncbi.nlm.nih.gov/pubmed/23133396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003025
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