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Phalloidin-induced cholestasis: a microfilament-mediated change in junctional complex permeability.

Phalloidin, administered to male rats for 7 days (500 microgram per kg/day), increased the mean hepatic content of filamentous actin. Both bile flow and bile acid excretion diminished proportionally, whereas the bile-to-plasma ratios of [3H]inulin and [14C]sucrose increased significantly from 0.08 a...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Elias, E, Hruban, Z, Wade, J B, Boyer, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6929547/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2229
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