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HIF-1α Inhibition Reduces Nasal Inflammation in a Murine Allergic Rhinitis Model
BACKGROUND: Hypoxia-inducible factor 1α (HIF-1α) is an important regulator of immune and inflammatory responses. We hypothesized that nasal allergic inflammation is attenuated by HIF-1α inhibition and strengthened by HIF-1α stabilization. OBJECTIVE: To elucidate the role of HIF-1α in a murine model...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486851/ https://ncbi.nlm.nih.gov/pubmed/23133644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048618 |
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