Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

Glutaraldehyde treatment of (125)I-labeled low density lipoprotein ((125)I-native-LDL) produced a modified LDL ((125)I-glut-LDL) with a molecular weight of 10 × 10(6) or more. Malondialdehyde treatment of (125)I-native-LDL produced a product ((125)I-MDA-LDL) with a molecular weight not appreciably d...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Fogelman, Alan M., Shechter, Ishaiahu, Seager, Janet, Hokom, Martha, Child, John S., Edwards, Peter A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1980
Schlagworte:	Biological Sciences: Medical Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6769124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2214
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