Immunoglobulin chain loss in hybridoma lines.
Hybrid cells secreting one, two, or three different immunoglobulins were constructed. The loss of immunoglobulin heavy or light chain expression was monitored. Chain loss was random only in lines with an excess of active light chain genes over heavy chain genes. In all other combinations preferentia...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1980
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6769123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2197 |
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