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A Step-by-step Method for the Reconstitution of an ABC Transporter into Nanodisc Lipid Particles
The nanodisc is a discoidal particle (~ 10-12 nm large) that trap membrane proteins into a small patch of phospholipid bilayer. The nanodisc is a particularly attractive option for studying membrane proteins, especially in the context of ligand-receptor interactions. The method pioneered by Sligar a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486754/ https://ncbi.nlm.nih.gov/pubmed/22951950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3910 |
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