Exon shuffling generates an immunoglobulin heavy chain gene.
From endonuclease EcoRI partial libraries of DNAs from mouse embryo and MOPC 141, a gamma 2b-producing myeloma, clones were isolated by using a DNA fragment carrying the gamma 2b constant (C) region gene as a hybridization probe. One clone from MOPC 141 contained a heavy chain variable (V) gene and...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6769120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2138 |
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