Peptidomimetic and Organometallic Derivatives of Primaquine Active against Leishmania infantum

The current treatment of visceral leishmaniasis is made difficult by the low efficacy, elevated costs, low bioavailability, and high toxicity of many of the available drugs. Primaquine, an antimalarial 8-aminoquinoline, displays activity against Leishmania spp., and several of its derivatives have b...

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Bibliographische Detailangaben
Hauptverfasser: Vale-Costa, Sílvia, Vale, Nuno, Matos, Joana, Tomás, Ana, Moreira, Rui, Gomes, Paula, Gomes, Maria Salomé
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486614/
https://ncbi.nlm.nih.gov/pubmed/22926569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00873-12
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