Identification of Peptides Derived from the Human Antimicrobial Peptide LL-37 Active against Biofilms Formed by Pseudomonas aeruginosa Using a Library of Truncated Fragments

Persistent Pseudomonas aeruginosa infections are a major cause of morbidity and mortality in cystic fibrosis (CF) patients and are linked to the formation of a biofilm. The development of new biofilm inhibition strategies is thus a major challenge. LL-37 is the only human antimicrobial peptide deriv...

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Detalhes bibliográficos
Main Authors: Nagant, C., Pitts, B., Nazmi, K., Vandenbranden, M., Bolscher, J. G., Stewart, P. S., Dehaye, J.-P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486595/
https://ncbi.nlm.nih.gov/pubmed/22908164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00918-12
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