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Immunocytochemistry for Vancomycin Using a Monoclonal Antibody That Reveals Accumulation of the Drug in Rat Kidney and Liver

We prepared monoclonal antibodies against N-(γ-maleimidobutyryloxy)succinimide-conjugated vancomycin (VM). The monoclonal antibody was specific for conjugated or free VM. The monoclonal antibody enabled us to develop an immunocytochemical method for detecting the uptake of VM in the rat kidney and l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fujiwara, Kunio, Yoshizaki, Yohei, Shin, Masashi, Miyazaki, Tsubasa, Saita, Tetsuya, Nagata, Shuichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486582/
https://ncbi.nlm.nih.gov/pubmed/22948874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01267-12
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