Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture.
In organ cultures of mammary glands from mice in midpregnancy, addition of both insulin and prolactin induces a marked accumulation of alpha-lactalbumin, whereas the augmentation of casein synthesis requires the presence of insulin, prolactin, and cortisol. Addition of 0.5 mM dibutyryl cyclic AMP re...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1980
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6154945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2093 |
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