Antibody-Independent Thrombocytopenia in Lactate Dehydrogenase-Elevating Virus-Infected Mice

Previously we demonstrated that antibody-mediated thrombocytopenia is strongly enhanced by lactate dehydrogenase-elevating virus (LDV) infection. Here we report that mice infected with LDV develop a moderate thrombocytopenia, even in the absence of immunoglobulins or Fc receptors. A similar decrease...

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Main Authors: Su, Dan, Musaji, Andrei, Legrain, Sarah, Detalle, Laurent, van der Kaa, Jos, Verbeek, J. Sjef, Ryffel, Bernhard, Coutelier, Jean-Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486507/
https://ncbi.nlm.nih.gov/pubmed/22933286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00745-12
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