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Rate theory calculation of gramicidin single-channel currents using NMR-derived rate constants.

By means of 23Na NMR, two ion binding sites were observed in phospholipid-packaged gramicidin channels and the four associated rate constants were approximated. Limits also were placed on a fifth rate constant for an intrachannel ion translocation. By using Eyring rate theory to introduce voltage de...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Urry, D W, Venkatachalam, C M, Spisni, A, Läuger, P, Khaled, M A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6154942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2028
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