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Differential Control of the Rate of 5′-End-Dependent mRNA Degradation in Escherichia coli

Many Escherichia coli mRNAs are degraded by a 5′-end-dependent mechanism in which RppH-catalyzed conversion of the 5′-terminal triphosphate to a monophosphate triggers rapid endonucleolytic cleavage by RNase E. However, little is understood about what governs the decay rates of these transcripts. We...

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Main Authors: Luciano, Daniel J., Hui, Monica P., Deana, Atilio, Foley, Patricia L., Belasco, Kevin J., Belasco, Joel G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486407/
https://ncbi.nlm.nih.gov/pubmed/22984254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01223-12
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