Modulation of Ribosomal Frameshifting Frequency and Its Effect on the Replication of Rous Sarcoma Virus

Programmed −1 ribosomal frameshifting is widely used in the expression of RNA virus replicases and represents a potential target for antiviral intervention. There is interest in determining the extent to which frameshifting efficiency can be modulated before virus replication is compromised, and we...

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Detalhes bibliográficos
Main Authors: Nikolić, Emily I. C., King, Louise M., Vidakovic, Marijana, Irigoyen, Nerea, Brierley, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486330/
https://ncbi.nlm.nih.gov/pubmed/22896611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01846-12
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