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Comparative Study of Influenza Virus Replication in MDCK Cells and in Primary Cells Derived from Adenoids and Airway Epithelium

Although clinical trials with human subjects are essential for determination of safety, infectivity, and immunogenicity, it is desirable to know in advance the infectiousness of potential candidate live attenuated influenza vaccine strains for human use. We compared the replication kinetics of wild-...

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Detalhes bibliográficos
Main Authors: Ilyushina, Natalia A., Ikizler, Mine R., Kawaoka, Yoshihiro, Rudenko, Larisa G., Treanor, John J., Subbarao, Kanta, Wright, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486302/
https://ncbi.nlm.nih.gov/pubmed/22915797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01477-12
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