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Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress

Transcription factor Nrf2 is considered a master regulator of antioxidant defense in mammals. However, it is unclear whether this concept is applicable to nonmammalian vertebrates, because no animal model other than Nrf2 knockout mice has been generated to examine the effects of Nrf2 deficiency. Her...

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Detalhes bibliográficos
Main Authors: Mukaigasa, Katsuki, Nguyen, Linh T. P., Li, Li, Nakajima, Hitomi, Yamamoto, Masayuki, Kobayashi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486152/
https://ncbi.nlm.nih.gov/pubmed/22949501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00481-12
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