GTPase ARFRP1 Is Essential for Normal Hepatic Glycogen Storage and Insulin-Like Growth Factor 1 Secretion

The GTPase ADP-ribosylation factor-related protein 1 (ARFRP1) is located at the trans-Golgi compartment and regulates the recruitment of Arf-like 1 (ARL1) and its effector golgin-245 to this compartment. Here, we show that liver-specific knockout of Arfrp1 in the mouse (Arfrp1(liv−/−)) resulted in e...

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Bibliografiska uppgifter
Huvudupphovsmän: Hesse, Deike, Jaschke, Alexander, Kanzleiter, Timo, Witte, Nicole, Augustin, Robert, Hommel, Angela, Püschel, Gerhard Paul, Petzke, Klaus-Jürgen, Joost, Hans-Georg, Schupp, Michael, Schürmann, Annette
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486143/
https://ncbi.nlm.nih.gov/pubmed/22927645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00522-12
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