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The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages

Here we report the isolation of 6 temperate bacteriophages (phages) that are prevented from replicating within the laboratory strain Pseudomonas aeruginosa PA14 by the endogenous CRISPR/Cas system of this microbe. These phages are only the second identified group of naturally occurring phages demons...

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Autori principali: Cady, Kyle C., Bondy-Denomy, Joe, Heussler, Gary E., Davidson, Alan R., O'Toole, George A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486085/
https://ncbi.nlm.nih.gov/pubmed/22885297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01184-12
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