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Construction and Evaluation of a Novel Recombinant T Cell Epitope-Based Vaccine against Coccidioidomycosis

Clinical and animal studies of coccidioidomycosis have demonstrated that activated CD4(+) T lymphocytes are essential for protection against this fungal respiratory disease. We previously reported a vaccine against Coccidioides infection which contained three recombinant CD4(+) T cell-reactive prote...

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Hlavní autoři: Hurtgen, Brady J., Hung, Chiung-Yu, Ostroff, Gary R., Levitz, Stuart M., Cole, Garry T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486067/
https://ncbi.nlm.nih.gov/pubmed/22949556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00566-12
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