Anaplasma phagocytophilum Outer Membrane Protein A Interacts with Sialylated Glycoproteins To Promote Infection of Mammalian Host Cells

Anaplasma phagocytophilum is the tick-transmitted obligate intracellular bacterium that causes human granulocytic anaplasmosis (HGA). A. phagocytophilum binding to sialyl Lewis x (sLe(x)) and other sialylated glycans that decorate P selectin glycoprotein 1 (PSGL-1) and other glycoproteins is critica...

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Auteurs principaux: Ojogun, Nore, Kahlon, Amandeep, Ragland, Stephanie A., Troese, Matthew J., Mastronunzio, Juliana E., Walker, Naomi J., VieBrock, Lauren, Thomas, Rachael J., Borjesson, Dori L., Fikrig, Erol, Carlyon, Jason A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486060/
https://ncbi.nlm.nih.gov/pubmed/22907813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00654-12
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