Pseudomonas aeruginosa Alkyl Quinolones Repress Hypoxia-Inducible Factor 1 (HIF-1) Signaling through HIF-1α Degradation

The transcription factor hypoxia-inducible factor 1 (HIF-1) has recently emerged to be a crucial regulator of the immune response following pathogen perception, including the response to the important human pathogen Pseudomonas aeruginosa. However, as mechanisms involved in HIF-1 activation by bacte...

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Main Authors: Legendre, Claire, Reen, F. Jerry, Mooij, Marlies J., McGlacken, Gerard P., Adams, Claire, O'Gara, Fergal
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486049/
https://ncbi.nlm.nih.gov/pubmed/22949552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00554-12
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