Titan Cell Production Enhances the Virulence of Cryptococcus neoformans

Infection with Cryptococcus neoformans begins when desiccated yeast cells or spores are inhaled and lodge in the alveoli of the lungs. A subset of cryptococcal cells in the lungs differentiate into enlarged cells, referred to as titan cells. Titan cells can be as large as 50 to 100 μm in diameter an...

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Bibliographic Details
Main Authors: Crabtree, Juliet N., Okagaki, Laura H., Wiesner, Darin L., Strain, Anna K., Nielsen, Judith N., Nielsen, Kirsten
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486048/
https://ncbi.nlm.nih.gov/pubmed/22890995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00507-12
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