Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces Soluble Tumor Necrosis Factor Receptor Production through Tumor Necrosis Factor Alpha-Converting Enzyme Activation

Primary Mycobacterium tuberculosis infection results in granuloma formation in lung tissue. A granuloma encapsulates mycobacterium-containing cells, thereby preventing dissemination and further infection. Tumor necrosis factor alpha (TNF-α) is a host-protective cytokine during M. tuberculosis infect...

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Main Authors: Richmond, Jillian M., Duffy, Elizabeth R., Lee, Jinhee, Kaboli, Kavon, Remick, Daniel G., Kornfeld, Hardy, Cruikshank, William W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486036/
https://ncbi.nlm.nih.gov/pubmed/22927046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00060-12
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