Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.

The heat-stable polypeptide ATP-dependent proteolysis factor 1 (APF-1) of the reticulocyte proteolytic system forms covalent compounds with proteins in an ATP-requiring reaction. APF-1 and lysozyme, a good substrate for ATP-dependent proteolysis, form multiple conjugates, as was shown by comigration...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hershko, A, Ciechanover, A, Heller, H, Haas, A L, Rose, I A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1980
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6990414/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.1783
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