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The Absence of PspA or Presence of Antibody to PspA Facilitates the Complement-Dependent Phagocytosis of Pneumococci In Vitro

Pneumococcal surface protein A (PspA) is a surface molecule on pneumococci that is required for full virulence in mouse models of infection. PspA has been reported to inhibit complement deposition on the pneumococcal surface. It has been assumed that this decreased complement deposition results in t...

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Main Authors: Ren, Bing, Li, Jie, Genschmer, Kristopher, Hollingshead, Susan K., Briles, David E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485889/
https://ncbi.nlm.nih.gov/pubmed/22855389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00393-12
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