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Antibody in Middle Ear Fluid of Children Originates Predominantly from Sera and Nasopharyngeal Secretions

The human middle ear is devoid of any immunocompetent cells in normal mucosa. We sought to determine the source of antibody present in the middle ear of children. Total IgG, IgA, and secretory IgA antibodies were determined by enzyme-linked immunosorbent assay from the nasopharyngeal, middle ear, an...

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Main Authors: Kaur, Ravinder, Kim, Thomas, Casey, Janet R., Pichichero, Michael E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485881/
https://ncbi.nlm.nih.gov/pubmed/22855395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05443-11
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