Variations in the Potassium Channel Genes KCNK3 and KCNK9 in Relation to Blood Pressure and Aldosterone Production: An Exploratory Study

CONTEXT: Two potassium (K) channel genes, Kcnk3 and Kcnk9, when deleted in mice, produced a model of hyperaldosteronism and hypertension. OBJECTIVE: Our objective was to explore genetic variation [single-nucleotide polymorphisms (SNP)] in KCNK3 and KCNK9 in relation to blood pressure (BP) and aldost...

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Hlavní autoři: Jung, Jeesun, Barrett, Paula Q., Eckert, George J., Edenberg, Howard J., Xuei, Xiaoling, Tu, Wanzhu, Pratt, J. Howard
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
JCEM Online: Advances in Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485591/
https://ncbi.nlm.nih.gov/pubmed/22893713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-2196
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