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Reactivation of ribosomal RNA genes in human-mouse hybrid cells by 12-O-tetradecanoylphorbol 13-acetate.

The effect of the potent tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) on the expression of rRNA genes was studied in human greater than mouse hybrid cells (55-54 cells). These hybrids retain the rRNA genes of both parent species but express only human rRNA. 55-54 cells were treated with...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Soprano, K J, Baserga, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246494/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.3.1566
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