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β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival

Extracellular matrix (ECM) integrity in the central nervous system (CNS) is essential for neuronal homeostasis. Signals from the ECM are transmitted to neurons through integrins, a family of cell surface receptors that mediate cell attachment to ECM. We have previously established a causal link betw...

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Bibliografiske detaljer
Main Authors: Santos, Andrea Rachelle C., Corredor, Raul G., Obeso, Betty Albo, Trakhtenberg, Ephraim F., Wang, Ying, Ponmattam, Jamie, Dvoriantchikova, Galina, Ivanov, Dmitry, Shestopalov, Valery I., Goldberg, Jeffrey L., Fini, Mary Elizabeth, Bajenaru, Michaela Livia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485184/
https://ncbi.nlm.nih.gov/pubmed/23118988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048332
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